AHK-Cu

AHK-Cu

High-Potency Tissue Remodeling & Angiogenic Research Compound

Product Overview

AHK-Cu (Copper Tripeptide-3) is a highly specialized peptide-copper complex recognized in biochemical research for its targeted role in vascular endothelial growth, extracellular matrix remodeling, and cellular signaling. Structurally composed of the amino acid sequence alanine-histidine-lysine coordinated with a copper ion, this compound is heavily investigated for its distinct ability to stimulate the secretion of vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF). In regenerative biology, AHK-Cu is a primary focus for studies exploring follicular cellular proliferation, localized angiogenesis, and collagen synthesis pathways.

Key Research Applications

• Angiogenesis & Endothelial Proliferation: Utilized in vascular biology models to study the upregulation of growth factors responsible for new blood vessel formation and localized microcirculation.

• Follicular Growth Regulation: Frequently studied in dermatological and trichological research models to evaluate its impact on elongating the anagen (growth) phase of hair follicles and suppressing follicular apoptosis pathways.

• Extracellular Matrix Synthesis: Investigated for its capacity to modulate fibroblasts, promoting the production of Collagen Type I and elastin while balancing matrix metalloproteinases (MMPs).

• Tissue Repair & Wound Models: Employed in preclinical tissue-engineering designs to observe cell migration and rate of structural dermal recovery following localized depletion or injury.

• Anti-Senescence Pathways: Evaluated in cellular longevity studies to observe how copper-binding complexes mitigate oxidative stress and improve structural integrity at the cellular level.

Why Researchers Choose AHK-Cu

• Targeted Follicular Specificity: Unlike broader copper complexes, AHK-Cu demonstrates high affinity for pathways governing follicular fibroblasts, offering a precise model for structural tissue research.

• High Analytical Purity: Our AHK-Cu is refined to a verified 99%+ purity, ensuring that experimental results remain precise and uncompromised by impurities or uncharacterized elements.

• Enhanced Structural Stability: Prepared to meet strict biochemical standards, facilitating dependable formulation and consistent dosing in both in vitro and in vivo experimental environments.

• Optimized Copper Bioavailability: Engineered for stable molecular coordination, ensuring the copper ion is effectively delivered to cellular receptors without premature dissociation.

Technical Specifications

• Molecular Formula: $C_{15}H_{24}CuN_{6}O_{4}$

• Molecular Weight: 415.94 g/mol

• Synonyms: Copper Tripeptide-3, Alanine/Histidine/Lysine Polypeptide Copper Complex

• Purity: 99%+

• Research Notice: AHK-Cu is strictly for laboratory and scientific research use only. It is not approved for human or animal consumption, medical treatment, or therapeutic use.

Storage & Handling Guide

To preserve the chemical stability and biological activity of AHK-Cu, please adhere to the following standard protocols:

• Temperature: For long-term storage, keep lyophilized powder stored in a freezer at -20°C. Once reconstituted, store immediately in a laboratory refrigerator at 2°C to 8°C.

• Environment: Protect from direct sunlight, excessive heat, and moisture. Avoid repeated freeze-thaw cycles after reconstitution to prevent structural degradation of the peptide chain.

• Handling: Use standard laboratory PPE, including Nitrile gloves and eye protection. Swirl gently during reconstitution—do not shake vigorously.

Research Use Only: This compound is intended for in vitro laboratory research and animal metabolic studies. It is not for human or clinical use.