DIHEXA

DIHEXA

High-Potency Cognitive Enhancement & Neurogenic Research Compound

Product Overview

Dihexa is an innovative, oligopeptide-derived compound developed to exhibit profound neuroprotective and neurogenic properties. In scientific literature, Dihexa is primarily recognized as a highly potent angiotensin IV analog that binds with high affinity to hepatocyte growth factor (HGF), potentiating its activity through its receptor, c-Met. This mechanism is heavily investigated for its ability to promote synaptogenesis—the formation of new synaptic connections between neurons—and facilitate dendritic arborization. Because of these unique structural impacts on neural architecture, Dihexa is a core focus for research involving cognitive enhancement, memory consolidation, and neurodegenerative models.

Key Research Applications

• Synaptogenesis & Dendritic Growth: Utilized in neurobiology models to observe the rapid formation of new functional synaptic connections and the extension of dendritic spines.

• Neurodegenerative Disease Models: Frequently studied in preclinical designs to evaluate its potential impact on reversing cognitive deficits associated with conditions like Alzheimer’s and Parkinson’s disease.

• Traumatic Brain Injury (TBI) Recovery: Investigated for its ability to accelerate cellular repair and functional recovery following mechanical neural trauma or ischemic injury.

• Cognitive Optimization & Memory: Employed in behavioral and metabolic studies to determine how enhancement of the HGF/c-Met pathway influences spatial learning, long-term memory retention, and overall processing speed.

• Neuroprotective Pathways: Evaluated for its capacity to protect existing neurons from oxidative stress, cellular toxicity, and apoptosis.

Why Researchers Choose DIHEXA

• Exceptional Potency: In comparative baseline studies, Dihexa has demonstrated synaptic structural enhancements that are orders of magnitude more potent than standard neurotrophic factors like BDNF.

• High Analytical Purity: Our Dihexa is refined to a verified 99%+ purity, ensuring that experimental results remain precise and uncompromised by impurities or uncharacterized elements.

• Enhanced Structural Stability: Prepared to meet strict biochemical standards, facilitating dependable formulation and consistent dosing in both in vitro and in vivo experimental environments.

• Blood-Brain Barrier Permeability: Extensively researched due to its structural capacity to effectively cross the blood-brain barrier, making it a highly reliable candidate for systemic or localized cognitive studies.

Technical Specifications

• Molecular Formula:  C27_H44_N4_O5

• Molecular Weight: 504.66 g/mol

• Synonyms: N-hexanoic-Tyr-Ile-6-aminohexanoic amide, PNP-5041

• Purity: 99%+

• Research Notice: Dihexa is strictly for laboratory and scientific research use only. It is not approved for human or animal consumption, medical treatment, or therapeutic use.

Storage & Handling Guide

To preserve the chemical stability and biological activity of Dihexa, please adhere to the following standard protocols:

• Temperature: For long-term storage, keep lyophilized powder stored in a freezer at -20°C. Once reconstituted, store immediately in a laboratory refrigerator at 2°C to 8°C.

• Environment: Protect from direct sunlight, excessive heat, and moisture. Avoid repeated freeze-thaw cycles after reconstitution to prevent structural degradation of the peptide chain.

• Handling: Use standard laboratory PPE, including Nitrile gloves and eye protection. Swirl gently during reconstitution—do not shake vigorously.

Research Use Only: This compound is intended for in vitro laboratory research and animal metabolic studies. It is not for human or clinical use.