AOD9604

Human Growth Hormone Fragment (177–191) & Metabolic Research Compound

Product Overview

AOD9604 is a specialized research peptide derived from the C-terminal end of the human growth hormone (hGH) sequence, specifically amino acids 177–191. This modified fragment is engineered to isolate the metabolic effects of hGH, allowing researchers to study lipid and glucose modulation without the secondary effects of IGF-1 activity. By acting through $\beta$-adrenergic and AMPK-related signaling, AOD9604 serves as a vital tool for exploring the mechanisms of energy regulation and adipocyte development.

Key Research Applications

• Lipid Metabolism Research: Valued for its ability to influence metabolic pathways and investigate the breakdown of lipids in experimental models.

• Adipocyte Differentiation: Targeted in studies exploring the life cycle of fat cells and the signaling involved in fat storage.

• Glucose Pathway Modulation: Frequently utilized to observe energy regulation without stimulating the IGF-1 growth axis.

• $\beta$-Adrenergic Signaling: Serves as a primary tool for exploring receptor-mediated metabolic responses.

• AMPK Mechanism Studies: Evaluated for its role in activating cellular energy sensors to maintain metabolic homeostasis.

Why Researchers Choose AOD9604

• Targeted Metabolic Action: Offers a specific way to study fat-related metabolism without the growth-promoting effects associated with full-length hGH.

• High Analytical Purity: Synthesized to a verified 99% HPLC purity to ensure high-fidelity results and batch-to-batch experimental consistency.

• Enhanced Stability: Provided in a lyophilized (powder) form for maximum chemical integrity during laboratory storage and transport.

Technical Specifications

• Molecular Formula: C78​_H123_​N23_​O23_​S2​

• Molecular Weight: 1815.1 g/mol

• Sequence: Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe

• CAS Number: 386264-39-7

Research Notice: AOD9604 is strictly for laboratory and scientific research use only. It is not approved for human or animal consumption, medical treatment, or therapeutic use.

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Validated Synthesis & Expedited Fulfillment

Clinical-Grade Synthesis & Purity

Our RUO peptides are engineered via precision synthesis, utilizing meticulously validated protocols to ensure uncompromising accuracy and batch-to-batch consistency. To maintain verified purity, every production lot undergoes independent third-party analysis—including HPLC and mass spectrometry—to confirm molecular identity and a purity of >99%. For expedited research timelines, we provide same-day fulfillment from our U.S. facility for orders placed before 12 PM PST, ensuring rapid and reliable delivery.

References:

1. Heffernan MA et al., Eur J Endocrinol, 2001 144:511-517

2. Ng FM et al., Drug Dev Res, 2000 51:63-71

3. Ng FM et al., Metabolism, 2002 51(12):1739-1743