B12

Vitamin B12

High-Potency Metabolic Coenzyme & Cellular Energy Research Compound

Product Overview

Vitamin B12 (specifically in its highly bioavailable form, Methylcobalamin) is a crucial water-soluble organometallic compound heavily utilized in metabolic, neurological, and hematological research. Featuring a complex corrin ring coordinated with a central cobalt ion, Vitamin B12 acts as an essential cofactor for key enzymatic reactions, including methionine synthase and methylmalonyl-CoA mutase. In cellular biology and metabolic models, this compound is primarily investigated for its fundamental role in DNA synthesis, erythrocyte maturation, fatty acid metabolism, and the maintenance of myelin structural integrity within the nervous system.

Key Research Applications

• Cellular Energy & ATP Production: Utilized in metabolic models to study the conversion of fats and carbohydrates into cellular energy via the citric acid cycle.

• DNA Synthesis & Methylation Pathways: Frequently studied in genetic and oncological research to evaluate its interaction with folate in the conversion of homocysteine to methionine, a critical step in cellular replication.

• Hematopoiesis & Red Blood Cell Maturation: Investigated in hematological designs to observe the proliferation and normal structural maturation of erythrocytes within bone marrow models.

• Neuroprotective & Myelin Maintenance: Employed in neurobiology to determine its impact on Schwann cells and the preservation of the myelin sheath protecting central and peripheral nerve fibers.

• Homocysteine Regulation: Studied in cardiovascular models to evaluate how efficient cobalamin pathways help regulate circulating homocysteine levels, a key marker of vascular endothelial stress.

Why Researchers Choose Vitamin B12

• Optimized Methylcobalamin Form: Unlike synthetic cyanocobalamin, the methylcobalamin variant requires no initial hepatic conversion, offering immediate biochemical availability for in vitro and in vivo research models.

• High Analytical Purity: Our Vitamin B12 is refined to a verified 99%+ purity, ensuring that experimental results remain precise and uncompromised by uncharacterized impurities or chemical stabilizers.

• Enhanced Structural Stability: Prepared to meet strict laboratory standards, ensuring consistent molecular integrity, dependable formulation stability, and predictable dosing.

• Fundamental Biological Baseline: Extensively researched as a foundational control or synergistic agent alongside cellular longevity, metabolic optimization, and tissue repair peptides.

Technical Specifications

• Molecular Formula:  C63_H91_Co_N14_O14_P

• Molecular Weight: 1344.4 g/mol

• Synonyms: Methylcobalamin, Mecobalamin, Coenzyme B12

• Purity: 99%+

• Research Notice: Vitamin B12 is strictly for laboratory and scientific research use only. It is not approved for human or animal consumption, medical treatment, or therapeutic use.

Storage & Handling Guide

To preserve the chemical stability and biological activity of Vitamin B12, please adhere to the following standard protocols:

• Temperature: For long-term storage, keep lyophilized powder stored in a freezer at -20°C. Once reconstituted, store immediately in a laboratory refrigerator at 2°C to 8°C.

• Environment: CRITICAL: Vitamin B12 is highly photosensitive. Protect strictly from direct sunlight and UV exposure. Store in amber vials or light-shielded environments, away from excessive heat and moisture.

• Handling: Use standard laboratory PPE, including Nitrile gloves and eye protection. Swirl gently during reconstitution—do not shake vigorously.

Research Use Only: This compound is intended for in vitro laboratory research and animal metabolic studies. It is not for human or clinical use.