CEREBROLYSIN

Neurotrophic Peptide Mixture & Neuroregenerative Signaling Research Compound

Product Overview

Cerebrolysin is a biotechnologically prepared peptide mixture consisting of low-molecular-weight neuropeptides and free amino acids purified from porcine brain proteins. In laboratory settings, it is utilized as a chemically defined tool to explore neurotrophic signaling, neuroprotective mechanisms, and synaptic plasticity. This peptide fraction is highly regarded in preclinical research for its role in investigating blood-brain barrier integrity, amyloid-beta modulation, and cellular defense systems under various neurodegenerative and ischemic stress conditions.

Key Research Applications

• Neurotrophic Signaling Modeling: Used in experimental workflows to study the activation of pathways similar to natural growth factors, including NGF, BDNF, CNTF, and GDNF.

• Neuroprotective Pathway Research: Targeted in studies exploring the defense of cortical and subcortical neurons from metabolic stress, apoptosis, and excitotoxicity.

• Synaptogenesis & Repair Studies: Utilized to quantify cellular and tissue-level structural remodeling, dendritic sprouting, and synaptic connection maintenance in specialized neural models.

• Amyloid-Beta & Tau Modulation: Frequently employed to measure interactions involving the minimization of amyloid-beta plaque accumulation and tau hyperphosphorylation.

• Glucose Transporter Regulation: Evaluated for its impact on glucose transport mechanisms GLUT-1 and blood-brain barrier preservation in ischemic research environments.

Why Researchers Choose Cerebrolysin

• Multifunctional Physiological Relevance: Mimics the multi-target actions of endogenous neurotrophic factors, providing a comprehensive subject for advanced cognitive research.

• High Analytical Purity: Isolate fraction processed to a verified 99% purity standard, ensuring maximum accuracy and reproducibility in sensitive laboratory assays.

• Stability-Focused Format: Available in a sterile solution or stable lyophilized form to maintain structural integrity and maximize shelf life during laboratory handling.

• Broad Neuro-Investigative Scope: Demonstrates multifaceted interactions across various central nervous system pathways in complex preclinical paradigms.

Technical Specifications

• Composition: Low-molecular-weight neuropeptides (peptides < 10kDa) and free amino acids.

• Molecular Formula: Complex multi-peptide isolate fraction.

• Molecular Weight: Varies by constituent low-molecular-weight peptide chains.

• CAS Number: 126132-83-2

• Purity: 99% Independent Isolate Verification.

• Research Notice: Cerebrolysin is strictly for laboratory and scientific research use only. It is not approved for human or animal consumption, medical treatment, or therapeutic use.

Validated Synthesis & Expedited Fulfillment

Clinical-Grade Synthesis & Purity

Our RUO peptides are engineered via precision isolation and synthesis, following meticulously validated protocols to ensure batch-to-batch consistency and uncompromising accuracy. To maintain verified purity, every production lot undergoes independent analytical testing—including HPLC and mass spectrometry—to confirm molecular identity and an isolate purity level of 99%. For expedited research timelines, we provide same-day fulfillment from our facility for orders placed before 12 PM PST.

References:

1. Sikiric P et al., Curr Pharm Des, 2018;24(18):2002–2030

2. Bornstein NM et al., Stroke, 2018;49(5):1214–1222

3. Alvarez XA et al., J Neural Transm, 2011;118(5):697–719

Storage & Handling Guide

To ensure the long-term stability and reproducibility of your experimental results, please follow these standardized laboratory protocols for Cerebrolysin:

I. Long-Term Storage (Unopened/Lyophilized)

• Temperature: Store at -20°C for long-term stability. The compound is stable at room temperature for short-term transit but should be frozen or refrigerated upon arrival per specific lot documentation.

• Environment: Keep in a cool, dry place away from direct light. Ensure the vial remains tightly sealed to prevent moisture contamination.

II. Reconstitution Protocol

• Solubility: Lyophilized fractions are highly soluble in sterile water, bacteriostatic water, or normal laboratory saline.

III. Storage of Liquid / Reconstituted Solution

• Short-Term: Once open or reconstituted, the sterile solution should be stored at 2°C to 8°C and utilized within 7 days.

• Long-Term: For extended use, aliquot the solution into single-use volumes and store at -20°C or -80°C.

• Avoid Freeze-Thaw Cycles: Repeated freezing and thawing significantly degrade peptide structure. Always use fresh aliquots for each assay.

Research Use Only: This compound is intended for in vitro laboratory research and animal imaging studies. It is not for human or clinical use.