REGEN-3 CHRONIC PAIN STACK: BPC-157 & ARA-290

Product Overview

This specialized research stack combines two extensively studied laboratory peptides—BPC-157 (a gastric-derived pentadecapeptide) and ARA-290 (a synthetic non-erythropoietic peptide derived from erythropoietin, also known as cibinetide)—into a chemically defined tool designed to explore synergistic tissue protection and neuropathic pain signaling pathways. In preclinical and cell-based models, this combination provides a multi-pathway approach to investigating innate repair receptor activation, cytokine modulation, and cellular stress responses.

Key Research Applications

• Targeted Neuroinflammatory & Pain Signaling: Investigates the combined capacity of BPC-157 and ARA-290 to modulate immune-mediated stress responses, interact with the innate repair receptor (IRR), and influence inflammatory pain pathways and tissue signaling endpoints.

• Tissue Protection & Cytoprotective Modeling: Explores the dual-action maintenance of cellular integrity, leveraging ARA-290’s well-documented tissue-protective mechanisms alongside BPC-157’s systemic cytoprotective pathways.

• Extracellular Matrix & Tissue Repair Modeling: Evaluates cytokine-regulated fibroblast signaling, collagen synthesis, and tissue remodeling under controlled experimental paradigms.

• Vascular & Growth Factor Pathways: Examines interactions with nitric oxide (NO) modulation and growth factor expression (such as VEGF) to study cellular protection against physiological and chemical stressors.

Why Researchers Choose This Formulation

• Complementary Mechanisms: Integrates the regenerative and cytoprotective properties of BPC-157 with the specialized tissue-protective and anti-inflammatory activity of ARA-290 for comprehensive pathway analysis.

• High Analytical Purity: Synthesized to a verified 99% HPLC purity, ensuring uncompromising accuracy and reproducibility in sensitive biochemical assays.

• Stability-Focused Format: Provided in a lyophilized (powder) form to maximize structural integrity and shelf life during laboratory handling and storage.

Technical Specifications

• Components: BPC-157 (Pentadecapeptide) + ARA-290 (Non-erythropoietic peptide, pyroGlu-Glu-Gln-Met-Tyr-Ser-Ile-Ala-His-Val-Lys-Trp-Lys-OH)

• Purity: 99% HPLC (Verified via independent analytical testing, including mass spectrometry)

• Format: Lyophilized powder

• Research Notice: Strictly for laboratory and scientific research use only. Not approved for human or animal consumption, medical treatment, or therapeutic use.

Storage & Handling Guide

To ensure the long-term stability of your experimental results, please follow these protocols:

I. Long-Term Storage (Lyophilized Powder)

• Temperature: Store at -20°C upon arrival.

• Environment: Keep in a cool, dry place away from direct light.

II. Reconstitution Protocol

• Solubility: Generally soluble in sterile water or aqueous buffers. It is recommended to use a sterile, preservative-free diluent.

III. Storage of Reconstituted Solution

• Short-Term: Store at 2°C to 8°C and use within 7 days.

• Long-Term: Aliquot into single-use volumes and store at -20°C to avoid repeated freeze-thaw cycles.