BPC-157

BPC-157

Gastric-Derived Peptide & Regenerative Signaling Research Compound

Product Overview

BPC-157 is a synthetic pentadecapeptide (15 amino acids) modeled after a naturally occurring protective protein fragment found in human gastric juice. In laboratory settings, it is utilized as a chemically defined tool to explore cytoprotective signaling, tissue repair mechanisms, and the modulation of nitric oxide pathways. This peptide is highly regarded in preclinical research for its role in investigating extracellular matrix remodeling and growth factor expression under various biological stress conditions.

Key Research Applications

• Angiogenic Signaling Modeling: Used in experimental workflows to study the formation of new blood vessels and vascular endothelial growth factor (VEGF) expression.

• Cytoprotective Pathway Research: Targeted in studies exploring the protection of cells and mucosal surfaces from chemically or physiologically induced damage.

• Molecular Repair Studies: Utilized to quantify cellular and tissue-level regenerative processes in specialized animal models.

• Nitric Oxide (NO) Modulation: Frequently employed to measure the peptide’s interaction with NO-mediated signaling and blood flow regulation.

• Extracellular Matrix (ECM) Remodeling: Evaluated for its impact on collagen synthesis and the structural integrity of connective tissues in research environments.

Why Researchers Choose BPC-157

• Biological Foundational Relevance: Derived from an endogenous gastric compound, providing a high-fidelity subject for physiological research.

• High Analytical Purity: Synthesized to a verified 99% HPLC purity, ensuring maximum accuracy and reproducibility in sensitive laboratory assays.

• Stability-Focused Format: Arrives in a lyophilized (powder) form to maintain structural integrity and maximize shelf life during laboratory handling.

• Broad Investigative Scope: Demonstrates multifaceted interactions across various organ systems and tissue types in preclinical paradigms.

Technical Specifications

• Amino Acid Sequence: Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val

• Molecular Formula: C62_H98_​N16_​O22​

• Molecular Weight: 1419.5 g/mol

• CAS Number: 137525-51-0

• Purity: 99% HPLC

• Research Notice: BPC-157 is strictly for laboratory and scientific research use only. It is not approved for human or animal consumption, medical treatment, or therapeutic use.

Validated Synthesis & Expedited Fulfillment

Clinical-Grade Synthesis & Purity

Our RUO peptides are engineered via precision synthesis, following meticulously validated protocols to ensure batch-to-batch consistency and uncompromising accuracy. To maintain verified purity, every production lot undergoes independent analytical testing—including HPLC and mass spectrometry—to confirm molecular identity and a purity level of 99%. For expedited research timelines, we provide same-day fulfillment from our facility for orders placed before 12 PM PST.

References:

• Sikiric P et al., Curr Pharm Des, 2018;24(18):2002–2030

• Kang EA et al., Dig Dis Sci, 2013;58:3310–3317

• Seiwerth S et al., Biomedicines, 2018;6(3):75

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Storage & Handling Guide

To ensure the long-term stability and reproducibility of your experimental results, please follow these standardized laboratory protocols for BPC-157:

I. Long-Term Storage (Lyophilized Powder)

• Temperature: Store at -20°C for long-term stability. The lyophilized format is stable at room temperature for short-term transit but should be frozen upon arrival.

• Environment: Keep in a cool, dry place away from direct light. Ensure the vial remains tightly sealed to prevent moisture absorption (hygroscopy).

II. Reconstitution Protocol

• Solubility: BPC-157 is soluble in sterile water or bacteriostatic water.

III. Storage of Reconstituted Solution

• Short-Term: Once reconstituted, the solution should be stored at 2°C to 8°C and used within 7 days.

• Long-Term: For extended use, aliquot the solution into single-use volumes and store at -20°C or -80°C.

• Avoid Freeze-Thaw Cycles: Repeated freezing and thawing significantly degrade peptide structure. Always use fresh aliquots for each assay.

Research Use Only: This compound is intended for in vitro laboratory research and animal imaging studies. It is not for human or clinical use.